Abstract
The purpose of this review article is to describe the history of photodynamic therapy (PDT), its current medical applications, the mechanism of action, contraindications of the method, and different types of photosensitizers used. The second part of the article deals with applications for gastrointestinal diseases. The treatment of obstructing oesophageal cancer, early-stage oesophageal cancer, Barretts esophagus, hilar cholangiocarcinoma, stomach-, colon- and pancreatic cancer are discussed. The final part focuses on future directions of PDT like certain innovative ideas, which are currently under investigation.
Keywords: photodynamic therapy, photosensitizers, gastrointestinal diseases, oesophageal cancer, pancreatic cancer
Current Pharmaceutical Biotechnology
Title: General Principles of Photodynamic Therapy (PDT) and Gastrointestinal Applications
Volume: 5 Issue: 4
Author(s): Marcus W. Wiedmann and Karel Caca
Affiliation:
Keywords: photodynamic therapy, photosensitizers, gastrointestinal diseases, oesophageal cancer, pancreatic cancer
Abstract: The purpose of this review article is to describe the history of photodynamic therapy (PDT), its current medical applications, the mechanism of action, contraindications of the method, and different types of photosensitizers used. The second part of the article deals with applications for gastrointestinal diseases. The treatment of obstructing oesophageal cancer, early-stage oesophageal cancer, Barretts esophagus, hilar cholangiocarcinoma, stomach-, colon- and pancreatic cancer are discussed. The final part focuses on future directions of PDT like certain innovative ideas, which are currently under investigation.
Export Options
About this article
Cite this article as:
Wiedmann W. Marcus and Caca Karel, General Principles of Photodynamic Therapy (PDT) and Gastrointestinal Applications, Current Pharmaceutical Biotechnology 2004; 5 (4) . https://dx.doi.org/10.2174/1389201043376805
DOI https://dx.doi.org/10.2174/1389201043376805 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Melatonin, Autophagy and Intestinal Bowel Disease
Current Pharmaceutical Design Effects of Iron Chelation in Osteosarcoma
Current Cancer Drug Targets Tumor-Receptor Imaging in Breast Cancer: A Tool for Patient Selection and Response Monitoring
Current Molecular Medicine PET/CT Based Dose Planning in Radiotherapy
Current Medical Imaging Monoclonal Antibodies in Allergy; Updated Applications and Promising Trials
Recent Patents on Inflammation & Allergy Drug Discovery Role of CCK/Gastrin Receptors in Gastrointestinal/Metabolic Diseases and Results of Human Studies Using Gastrin/CCK Receptor Agonists/Antagonists in these Diseases
Current Topics in Medicinal Chemistry Modulation of Neutrophil Function by Hormones
Current Immunology Reviews (Discontinued) The Role of Epidermal Growth Factor Receptor in the Management of Gastrointestinal Carcinomas: Present Status and Future Perspectives
Current Pharmaceutical Design Coordinated Expression of Pax-5 and FAK1 in Metastasis
Anti-Cancer Agents in Medicinal Chemistry miRNAs in Gastrointestinal and Liver Cancers: Their Perspectives and Clinical Applications
Current Pharmaceutical Design Adhesion Molecules as Targets for the Treatment of Neoplastic Diseases
Current Pharmaceutical Design Metabolic Profiling in Disease Diagnosis, Toxicology and Personalized Healthcare
Current Pharmaceutical Biotechnology Impact of Curcumin on Microsomal Enzyme Activities: Drug Interaction and Chemopreventive Studies
Current Medicinal Chemistry Recent Advances in the Development of Multi-Kinase Inhibitors
Mini-Reviews in Medicinal Chemistry Anticancer Therapeutic Strategies Based on CDK Inhibitors
Current Pharmaceutical Design Carotenoids and Modulation of Cancer: Molecular Targets
Current Pharmacogenomics The Role of Protein Kinase C-alpha (PKC-α) in Cancer and its Modulation by the Novel PKC-α-Specific Inhibitor Aprinocarsen
Current Pharmaceutical Design Overview of the Formulations and Analogs in the Taxanes' Story
Current Medicinal Chemistry COVID-19 Invades Several Important Organs other than the Lungs: Organs Crosstalk
Coronaviruses PDE5 Inhibitor Treatment Options for Urologic and Non-Urologic Indications: 2012 Update
Current Pharmaceutical Design