Abstract
An efficient, mild, cost effective and eco-friendly synthesis of 2,3- dihydroquinazoline- 4(1H)-ones is described in which isatoic anhydride, primary amines and variety of aldehydes react in the presence of citric acid as a green, bioorganic and inexpensive catalyst via rapid one-pot threecomponent reaction in boiling ethanol.
Keywords: Aldehydes, bioorganic catalyst, citric acid, 2, 3-dihydroquinazoline-4(1H)-ones, isatoic anhydride, multicomponent synthesis, primary amines.
Graphical Abstract
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