摘要
炎症已被确认为心血管疾病进程的一个重要决定因素。目前,为诊断、预后和疾病监测的临床检查、实验室和影像学测试是非常重要的。新型炎症生物标记物也被用于更好地再分类风险组患者,但它们指导治疗决策和患者管理的潜能尚未被广泛评估。因此,本文就心血管治疗中炎症生物标记物的使用提出最新数据。
关键词: 动脉粥样硬化,生物标记物,心血管疾病,冠心病,心力衰竭,高血压,炎症,外周动脉疾病,中风。
Current Medicinal Chemistry
Title:Novel Inflammatory Biomarkers in Cardiovascular Therapeutics
Volume: 22 Issue: 23
Author(s): Vicky Tsigkou, Gerasimos Siasos, Evangelos Oikonomou, Marina Zaromitidou, George Latsios, Manolis Vavuranakis, Spyridon Deftereos, Michael W. Cleman, Eleni Kokkou, Maria Limberi, Stathis Dimitropoulos,, Thodoris Zografos, Smaragdi Marinaki, Christodoulos Stefanadis and Dimitris Tousoulis
Affiliation:
关键词: 动脉粥样硬化,生物标记物,心血管疾病,冠心病,心力衰竭,高血压,炎症,外周动脉疾病,中风。
摘要: Inflammation has been established as an important determinant of cardiovascular disease progression. Currently, clinical examination, laboratory and imaging tests are invaluable for the diagnosis, prognosis and disease monitoring. Novel inflammatory biomarkers are also used to better restratify patients in risk groups but their potential to guide treatment decisions and management of patients has not been extensively evaluated. Therefore, in this review article we present the most recent data concerning the use of inflammatory biomarkers in cardiovascular therapeutics.
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Vicky Tsigkou , Gerasimos Siasos , Evangelos Oikonomou , Marina Zaromitidou , George Latsios , Manolis Vavuranakis , Spyridon Deftereos , Michael W. Cleman , Eleni Kokkou , Maria Limberi , Stathis Dimitropoulos, , Thodoris Zografos , Smaragdi Marinaki , Christodoulos Stefanadis and Dimitris Tousoulis , Novel Inflammatory Biomarkers in Cardiovascular Therapeutics, Current Medicinal Chemistry 2015; 22 (23) . https://dx.doi.org/10.2174/0929867322666150429110124
DOI https://dx.doi.org/10.2174/0929867322666150429110124 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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