Abstract
Pectin and its modified forms have been used in the formulation of controlled and sustained drug delivery systems in recent years. Due to its biodegradability, easy availability and other benefits it is one of the first choices for both consumers and research scientists. Ease in modifications of the acidic group into amide, ester or other forms leads to the alterations in physical and chemical properties of pectin which further increases its significance. Formulations based on pectin and its modified forms have shown a tremendous promise as novel biomaterials for targeting of the drugs and other emerging biomedical applications. Also pectin based products are utilized in cosmetic, textile and food industries. In this review we have summarized the sources of pectin, various extraction procedures, patents and different approaches to modify physio-chemical properties of pectin affecting the drug release. This paper emphasizes the practical utility of pectin and its modified form in pharmaceutical dosage forms.
Keywords: Drug release, modified pectin, patents, pectin, pharmaceuticals.
Graphical Abstract
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