Abstract
The present critical review is related to the self-modified patch based drug delivery system for controlled (trans) dermal drug delivery. The composition itself is modified into the patch and adheres when comes in contact with the skin and acts as a rate-controlling matrix layer (patch). The self adhesiveness property of the formulation itself is enough to hold the patch in place on the skin for the - duration of treatment while allowing the patch to be promptly backed by without any skin irritation and formulation residue. This patent review is useful for the knowledge of self modified patch associated drug delivery for controlled topical or transdermal delivery of pharmaceutical and cosmetic agents.
Keywords: Bioadhesive, film forming polymers, patch in can, rate-controlling matrix layer, self-modified patch.