摘要
基于RNAi的疗法认为有前景成为anti-gene领域有效的治疗应用策略。然而,尽管它拥有巨大的潜力, 但是其发展面临各种困扰,其全部功能无法实现真正的意义。需要努力推动具体而有效的发展策略来克服临床上至关重要的约束。本文陈述了当前成功将siRNA翻译由概念变成现实的主要障碍以及努力攻克这些难关而正在进行的一些研究。
关键词: 抗基因,有效的,RNAi,安全,治疗
Current Gene Therapy
Title:SiRNA Nanotherapeutics _The Panacea of Diseases?
Volume: 15 Issue: 2
Author(s): Khan Farheen Badrealam, Swaleha Zubair and Mohammad Owais
Affiliation:
关键词: 抗基因,有效的,RNAi,安全,治疗
摘要: RNAi based therapeutics hold s great promises to be an efficient strategy of the anti-gene realm in context of its therapeutic applications; however, despite significant potentials, its full efficacy cannot be realized in real sense owing to various confronts that plague its advancement. Efforts need to be driven for the development of specific and efficacious strategies to subdue some of their crucial constraints towards successes in clinics. This article will present the major impediments that encumber successful translation of siRNA concept into reality and the ongoing research endeavours to get through those stumbling blocks along with their inadequacies.
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Cite this article as:
Khan Farheen Badrealam, Swaleha Zubair and Mohammad Owais , SiRNA Nanotherapeutics _The Panacea of Diseases?, Current Gene Therapy 2015; 15 (2) . https://dx.doi.org/10.2174/1566523215666150122130047
DOI https://dx.doi.org/10.2174/1566523215666150122130047 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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