光学分子成像的新进展和它在靶向给药中的应用

Title:Recent Advances in Optical Molecular Imaging and its Applications in Targeted Drug Delivery

Volume: 16 Issue: 6

Author(s): Xibo Ma, Hui Hui, Wenting Shang, Xiaohua Jia, Xin Yang and Jie Tian

Affiliation:

关键词: 光学分子成像，靶向给药，生物发光成像，荧光成像，双光子显微成像，拉曼成像。

摘要: Optical molecular imaging has been frequently used in many preclinical researches including cancer detection, tumor mechanism study, drug efficacy evaluation and targeted drug delivery. Among optical molecular imaging modalities, bioluminescence imaging and fluorescence imaging have acquired certain degree of development and attracted more and more attention in recent years for their high sensitivity and low cost. With the development of optical technology and probe technology, two-photon microscopy imaging and Raman imaging have been widely used in drug evaluation and tumor studies through cell and tissue imaging. This paper focuses on the occurrence and development of optical molecular imaging especially for its imaging method imaging system and its application in target drug delivery. Finally, the existing challenges and brand new applications of optical imaging techniques in drug delivery research are discussed.

Cite this article as:

Xibo Ma, Hui Hui, Wenting Shang, Xiaohua Jia, Xin Yang and Jie Tian , Recent Advances in Optical Molecular Imaging and its Applications in Targeted Drug Delivery, Current Drug Targets 2015; 16 (6) . https://dx.doi.org/10.2174/1389450116666150102112747