摘要
以前的研究调查轻度认知障碍(MCI)主要集中在认知、记忆、注意力和执行功能减退。目前已有的对知觉减退可能会出现MCI的研究相对较少。这是令人惊讶的,因为已知感觉和认知功能共享一个共同的皮质框架[1]。在下面的研究中,我们通过声致闪光错觉(SIFI)引起一组参与者轻度认知障碍(MCI)和健康对照(HC)进行测试。SIFI是一个视听幻觉,由两蜂鸣器和一个闪光组成。参与者倾向于感知到2次闪烁当蜂鸣的哔哔时间间隔很短时[2,3]。有MCI的参与者更显著错觉,相比HC在较长的蜂鸣时间间隔下。这表明,与HC相比,MCI患者收集到更多的(可以说是无关紧要的)视听资料。通过将感知任务转化为一个临床诊断有可能获得对疾病更全面的了解,以及提供更准确的诊断哪些人可能患有语言障碍。
关键词: 轻度认知损伤,多传感器集成,声音诱导闪光错觉。
Current Alzheimer Research
Title:Expanded Temporal Binding Windows in People with Mild Cognitive Impairment
Volume: 12 Issue: 1
Author(s): Jason S. Chan, Jochen Kaiser, Mareike Brandl, Silke Matura, David Prvulovic, Michael J. Hogan and Marcus J. Naumer
Affiliation:
关键词: 轻度认知损伤,多传感器集成,声音诱导闪光错觉。
摘要: Previous studies investigating mild cognitive impairment (MCI) have focused primarily on cognitive, memory, attention, and executive function deficits. There has been relatively little research on the perceptual deficits people with MCI may exhibit. This is surprising given that it has been suggested that sensory and cognitive functions share a common cortical framework [1]. In the following study, we presented the sound-induced flash illusion (SiFi) to a group of participants with mild cognitive impairment (MCI) and healthy controls (HC). The SiFi is an audio-visual illusion whereby two-beeps and one-flash are presented. Participants tend to perceive two flashes when the time-interval between the auditory beeps is small [2, 3]. Participants with MCI perceived significantly more illusions compared to HC over longer auditory time-intervals. This suggests that MCIs integrate more (arguably irrelevant) audiovisual information compared to HCs. By incorporating perceptual tasks into a clinical diagnosis it may be possible to gain a more comprehensive understanding into the disease, as well as provide a more accurate diagnose to those who may have a language impairment.
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Jason S. Chan, Jochen Kaiser, Mareike Brandl, Silke Matura, David Prvulovic, Michael J. Hogan and Marcus J. Naumer , Expanded Temporal Binding Windows in People with Mild Cognitive Impairment, Current Alzheimer Research 2015; 12 (1) . https://dx.doi.org/10.2174/1567205012666141218124744
DOI https://dx.doi.org/10.2174/1567205012666141218124744 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
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