Abstract
Cystic fibrosis (CF) is a genetic disorder that can lead to death at an early age. CF is characterized by respiratory infection, airway obstruction, inflammation, and eventually end-stage lung failure. CF also damages pancreatic exocrine function resulting in serious complications such as nutritional deficiencies. Current therapy to this multisystem disease requires the practice of both pharmacological and nutritional approaches. Growing evidence shows that bioactive food components, such as polyunsaturated fatty acids, phytochemicals, and antioxidants, have beneficial effects in the management of CF disease. This review will summarize the current status of bioactive compounds in CF therapy.
Keywords: Antioxidant, bioactive food component, cystic fibrosis, functional food, nutraceutical, polyunsaturated fatty acid, phytochemical.
Graphical Abstract
Current Drug Targets
Title:Bioactive Food Components as Dietary Intervention for Cystic Fibrosis
Volume: 16 Issue: 9
Author(s): Nualpun Sirinupong and Zhe Yang
Affiliation:
Keywords: Antioxidant, bioactive food component, cystic fibrosis, functional food, nutraceutical, polyunsaturated fatty acid, phytochemical.
Abstract: Cystic fibrosis (CF) is a genetic disorder that can lead to death at an early age. CF is characterized by respiratory infection, airway obstruction, inflammation, and eventually end-stage lung failure. CF also damages pancreatic exocrine function resulting in serious complications such as nutritional deficiencies. Current therapy to this multisystem disease requires the practice of both pharmacological and nutritional approaches. Growing evidence shows that bioactive food components, such as polyunsaturated fatty acids, phytochemicals, and antioxidants, have beneficial effects in the management of CF disease. This review will summarize the current status of bioactive compounds in CF therapy.
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Cite this article as:
Sirinupong Nualpun and Yang Zhe, Bioactive Food Components as Dietary Intervention for Cystic Fibrosis, Current Drug Targets 2015; 16 (9) . https://dx.doi.org/10.2174/1389450115666141122211111
DOI https://dx.doi.org/10.2174/1389450115666141122211111 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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