Abstract
A highly efficient method for synthesis of multifunctionalized benzenes by one-pot multicomponent condensation between malononitrile, substituted aldehyde and cycloheptanone catalyzed by Zn-VCO3 hydrotalcite is reported. With water as solvent, this green chemistry reaction entails mild conditions. It is atom-efficient, high-yielding and pertinent to an extensive variety of multicomponent reactions.
Keywords: Green chemistry, multicomponent reaction, multifunctionalized benzenes, reusable catalyst, water as a solvent, Zn-VCO3 hydrotalcite.
Graphical Abstract
Current Organic Synthesis
Title:Multicomponent Reactions in Water Medium Catalyzed by Zn-VCO3 Hydrotalcite: A Greener and Efficient Approach for the Synthesis of Multifunctionalized Benzenes
Volume: 12 Issue: 2
Author(s): Ramakanth Pagadala, Suresh Maddila, Surjyakanta Rana and Sreekantha B. Jonnalagadda
Affiliation:
Keywords: Green chemistry, multicomponent reaction, multifunctionalized benzenes, reusable catalyst, water as a solvent, Zn-VCO3 hydrotalcite.
Abstract: A highly efficient method for synthesis of multifunctionalized benzenes by one-pot multicomponent condensation between malononitrile, substituted aldehyde and cycloheptanone catalyzed by Zn-VCO3 hydrotalcite is reported. With water as solvent, this green chemistry reaction entails mild conditions. It is atom-efficient, high-yielding and pertinent to an extensive variety of multicomponent reactions.
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Cite this article as:
Pagadala Ramakanth, Maddila Suresh, Rana Surjyakanta and Jonnalagadda B. Sreekantha, Multicomponent Reactions in Water Medium Catalyzed by Zn-VCO3 Hydrotalcite: A Greener and Efficient Approach for the Synthesis of Multifunctionalized Benzenes, Current Organic Synthesis 2015; 12 (2) . https://dx.doi.org/10.2174/1570179411999141106101741
DOI https://dx.doi.org/10.2174/1570179411999141106101741 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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