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Current Cardiology Reviews

Editor-in-Chief

ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

Clinical and Experimental Evidence of Supernormal Excitability and Conduction

Author(s): Marcelo V. Elizari, Jorge Schmidberg, Augusto Atienza, Diego V. Paredes and Pablo A. Chiale

Volume 10, Issue 3, 2014

Page: [202 - 221] Pages: 20

DOI: 10.2174/1573403X1003140522161728

Price: $65

Abstract

True supernormality of excitability and conduction has been demonstrated in normal Purkinje fibers in in vitro studies. In the clinical setting, supernormality of conduction is manifested better than expected. This phenomenon is much more common than previously thought, particularly in the presence of certain clinical conditions. If a careful scanning of the cardiac cycle is performed on all patients with intermittent bundle branch block and second degree or advanced infranodal AV block, accessory pathways and mulfunctioning pacemakers, it is anticipated that a much larger amount of supernormal excitability and conduction will be unmasked.

Keywords: Arrythmias, AV block, intermittent bundle branch block, Mobitz type II AV block, supernormality, ventricular pre-excitation.


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