摘要
与一些慢性疾病相似,儿童初期的动脉高血压(HTN)的血压读数经常、反复超过该人群标准血压的百分数值高于95。在日常生活中,血压一般以相同的百分数值存在,拥有较高血压值的孩子更倾向于成为高血压患者。在通过减重、有氧体育运动、低钠摄入等健康措施来降低血压不起作用后,药物治疗则必不可少。该文对儿童降压药物治疗进行了综述,调查了长期高血压和高血压危象(如患病儿童多数情况下血压百分位数值高于99)经药物治疗后效果。并对美国和欧洲儿童高血压治疗方法的一些显著区别进行了深刻地分析。
关键词: 血压,儿童用药,指导方针,儿科高血压,治疗
Current Medicinal Chemistry
Title:Antihypertensive Therapy in Children: Differences in Medical Approach Between the United States and Europe
Volume: 21 Issue: 27
Author(s): P. P. Bassareo, V. Bassareo, N. Iacovidou and G. Mercuro
Affiliation:
关键词: 血压,儿童用药,指导方针,儿科高血压,治疗
摘要: Similarly to a series of chronic diseases, essential arterial hypertension (HTN) may be manifested during childhood as a blood pressure (BP) reading which repeatedly rises above the 95th percentile of population-specific standards. Since BP tends to track along the same percentiles throughout life, children with higher BPs are more likely to become hypertensive adults. When healthy measures aimed at reducing BP (i.e. body weight reduction, aerobic physical exercise, low sodium intake) have failed, pharmacological treatment is usually required. This paper aims to undertake a review of antihypertensive pharmacological therapy in children, examining the drugs used in chronic treatment as well as those administered to treat hypertensive crisis (i.e. a BP major than 99th percentile of paediatric normograms). Moreover, several important differences registered in the therapeutic approach to paediatric HTN between US and European Guidelines will be underlined.
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Cite this article as:
Bassareo P. P., Bassareo V., Iacovidou N. and Mercuro G., Antihypertensive Therapy in Children: Differences in Medical Approach Between the United States and Europe, Current Medicinal Chemistry 2014; 21 (27) . https://dx.doi.org/10.2174/0929867321666140304093848
DOI https://dx.doi.org/10.2174/0929867321666140304093848 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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