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Cardiovascular & Hematological Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5257
ISSN (Online): 1875-6182

Cardioprotective Effect of Resveratrol and Resveratroloside

Author(s): Sergey E. Naumenko, Tatiana V. Latysheva, Michael A. Gilinsky, Artem D. Rogachev, Nina I. Komarova, Nariman F. Salakhutdinov and Genrikh A. Tolstikov

Volume 11, Issue 3, 2013

Page: [207 - 210] Pages: 4

DOI: 10.2174/187152571103140120103302

Price: $65

Abstract

Cardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received resveratroloside). The cardioprotective effect of resveratroloside was detected for the first time.

Keywords: Cardiovascular disease, in vivo experiments, ischemia-reperfusion, myocardial infarction, myocardial ischemia, natural stilbenes, Pinus sibirica, preconditioning, resveratrol, resveratroloside.


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