Abstract
Schizophrenia is a major mental illness that is characterized by psychosis, apathy, social withdrawal and cognitive impairment. These abnormalities in patients results in impaired functioning in work, school, parenting, self-care, independent living, interpersonal relationships, and leisure. Although the search for the biological correlates of schizophrenia has met with limited success, new advances in genetics and pharmacology are promising. Here, we describe the symptoms, causes, diagnosis, strategies for treatment, and clinical impact of the currently available medications.
Keywords: Positive symptoms, negative symptoms, cognitive symptoms, brain circuits, dopamine, glutamate, genes, environmental factors, clinical criterias, imaging, typical antipsychotics, atypical antipsychotics.
Current Pharmaceutical Design
Title:Schizophrenia: Causes and Treatments
Volume: 19 Issue: 36
Author(s): Zafar U. Khan, Elisa Martin-Montañez and E. Chris Muly
Affiliation:
Keywords: Positive symptoms, negative symptoms, cognitive symptoms, brain circuits, dopamine, glutamate, genes, environmental factors, clinical criterias, imaging, typical antipsychotics, atypical antipsychotics.
Abstract: Schizophrenia is a major mental illness that is characterized by psychosis, apathy, social withdrawal and cognitive impairment. These abnormalities in patients results in impaired functioning in work, school, parenting, self-care, independent living, interpersonal relationships, and leisure. Although the search for the biological correlates of schizophrenia has met with limited success, new advances in genetics and pharmacology are promising. Here, we describe the symptoms, causes, diagnosis, strategies for treatment, and clinical impact of the currently available medications.
Export Options
About this article
Cite this article as:
Khan U. Zafar, Martin-Montañez Elisa and Muly Chris E., Schizophrenia: Causes and Treatments, Current Pharmaceutical Design 2013; 19 (36) . https://dx.doi.org/10.2174/1381612811319360006
DOI https://dx.doi.org/10.2174/1381612811319360006 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Impact of Methodology and Confounding Variables on the Association Between Major Depression and Coronary Heart Disease: Review and Recommendations
Current Psychiatry Reviews Does Pharmacological Therapy Still Play a Role in Preventing Sudden Death in Surgically Treated Tetralogy of Fallot?
Mini-Reviews in Medicinal Chemistry Molecular Dissection of Renal Ischemia-Reperfusion: Oxidative Stress and Cellular Events
Current Medicinal Chemistry Phosphorothioate Oligonucleotides: Effectiveness and Toxicity
Current Drug Targets The Adult Patient with Eisenmenger Syndrome: A Medical Update after Dana Point Part II: Medical Treatment - Study Results
Current Cardiology Reviews Adenosine and ATP Receptors in the Brain
Current Topics in Medicinal Chemistry An Update on Disease Modifying Antirheumatic Drugs
Inflammation & Allergy - Drug Targets (Discontinued) Thrombotic Thrombocytopenic Purpura, from the Perspectives of a Pediatrician
Current Pediatric Reviews Management of Acute Aluminum Phosphide Poisoning: Has Anything Changed?
Drug Metabolism Letters Acute Decompensated Heart Failure Update
Current Cardiology Reviews Management of Food-Induced Anaphylaxis: Unsolved Challenges
Current Clinical Pharmacology Emerging Roles for Connexins in Hypertension
Current Hypertension Reviews Effects of Estrogen in Gender-dependent Fetal Programming of Adult Cardiovascular Dysfunction
Current Vascular Pharmacology Editorial: [Hot Topic: Chromogranin A at the Crossroads of Health and Disease]
Current Medicinal Chemistry Urtica dioica in the Management of Benign Prostate Hyperplasia (BPH)
The Natural Products Journal Standardization Using Analytical Techniques (UV, NMR, FTIR, HPLC, Mass) and Pharmacognostic Evaluation of the Roots of <i>Selinum vaginatum</i>: A Rare Himalayan Plant of the Rohtang Region
Current Biotechnology The Effect of Serotonin 5-HT2 Receptor Inhibitor on Vasomotor Responses
Vascular Disease Prevention (Discontinued) Potential Benefits of Glitazones for Cancer and Vascular Disease
Current Drug Therapy Adrenocortical Crisis Triggered by Levothyroxine in an Unrecognized Autoimmune Polyglandular Syndrome Type-2: A Case Report with Review of the Literature
Current Drug Safety Mesenchymal Stem Cells as a Source of Dopaminergic Neurons: A Potential Cell Based Therapy for Parkinson's Disease
Current Stem Cell Research & Therapy