Abstract
This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in 11C and 18F-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.
Keywords: PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18.
Current Pharmaceutical Design
Title:Small Molecule PET-Radiopharmaceuticals
Volume: 20 Issue: 14
Author(s): Philip H. Elsinga and Rudi A.J.O. Dierckx
Affiliation:
Keywords: PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18.
Abstract: This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in 11C and 18F-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.
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Cite this article as:
Elsinga H. Philip and Dierckx A.J.O. Rudi, Small Molecule PET-Radiopharmaceuticals, Current Pharmaceutical Design 2014; 20 (14) . https://dx.doi.org/10.2174/13816128113196660661
DOI https://dx.doi.org/10.2174/13816128113196660661 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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