Nanocarriers for Anticancer Drugs - New Trends in Nanomedicine

Title:Nanocarriers for Anticancer Drugs - New Trends in Nanomedicine

Volume: 14 Issue: 5

Author(s): Jana Drbohlavova, Jana Chomoucka, Vojtech Adam, Marketa Ryvolova, Tomas Eckschlager, Jaromir Hubalek and Rene Kizek

Affiliation:

Keywords: Nanotechnologies, nanoparticles, gene therapy, anticancer drugs, drug carriers, cancer, cytostatic, targeted therapy.

Abstract: This review provides a brief overview of the variety of carriers employed for targeted drug delivery used in cancer therapy and summarizes advantages and disadvantages of each approach. Particularly, the attention was paid to polymeric nanocarriers, liposomes, micelles, polyethylene glycol, poly(lactic-co-glycolic acid), dendrimers, gold and magnetic nanoparticles, quantum dots, silica nanoparticles, and carbon nanotubes. Further, this paper briefly focuses on several anticancer agents (paclitaxel, docetaxel, camptothecin, doxorubicin, daunorubicin, cisplatin, curcumin, and geldanamycin) and on the influence of their combination with nanoparticulate transporters to their properties such as cytotoxicity, short life time and/or solubility.

Cite this article as:

Drbohlavova Jana, Chomoucka Jana, Adam Vojtech, Ryvolova Marketa, Eckschlager Tomas, Hubalek Jaromir and Kizek Rene, Nanocarriers for Anticancer Drugs - New Trends in Nanomedicine, Current Drug Metabolism 2013; 14 (5) . https://dx.doi.org/10.2174/1389200211314050005