Abstract
Sucrose hydrolytic enzymes, widely used in a variety of food industries, employ sucrose as a substrate. In addition to their hydrolysis activities, they have other recently discovered characteristics that should make them useful for medical applications. Here, the two enzymes sucrose phosphorylase and invertase are discussed. Sucrose phosphorylase glycosylates non-carbohydrate small molecules and invertase can be used in a portable and personal biosensor to quantify a variety of analytical targets.
Keywords: Sucrose phosphorylase, Invertase, transglycosylation, non-carbohydrate transglycosylation, Biosensor, glucose meter.
Current Topics in Medicinal Chemistry
Title:Sucrose Hydrolytic Enzymes: Old Enzymes for New Uses as Biocatalysts for Medical Applications
Volume: 13 Issue: 10
Author(s): Hao Pang, Liqin Du, Jianxin Pei, YuTuo Wei, Qishi Du and Ribo Huang
Affiliation:
Keywords: Sucrose phosphorylase, Invertase, transglycosylation, non-carbohydrate transglycosylation, Biosensor, glucose meter.
Abstract: Sucrose hydrolytic enzymes, widely used in a variety of food industries, employ sucrose as a substrate. In addition to their hydrolysis activities, they have other recently discovered characteristics that should make them useful for medical applications. Here, the two enzymes sucrose phosphorylase and invertase are discussed. Sucrose phosphorylase glycosylates non-carbohydrate small molecules and invertase can be used in a portable and personal biosensor to quantify a variety of analytical targets.
Export Options
About this article
Cite this article as:
Pang Hao, Du Liqin, Pei Jianxin, Wei YuTuo, Du Qishi and Huang Ribo, Sucrose Hydrolytic Enzymes: Old Enzymes for New Uses as Biocatalysts for Medical Applications, Current Topics in Medicinal Chemistry 2013; 13 (10) . https://dx.doi.org/10.2174/15680266113139990010
DOI https://dx.doi.org/10.2174/15680266113139990010 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Molecular Targets of Mesalazine in Colorectal Cancer
Current Cancer Therapy Reviews Highlights in Peptide Nanoparticle Carriers Intended to Oral Diseases
Current Topics in Medicinal Chemistry Current and Potential Anticancer Drugs Targeting Members of the UHRF1 Complex Including Epigenetic Modifiers
Recent Patents on Anti-Cancer Drug Discovery 1,3,5-Triazine Analogs: A Potent Anticancer Scaffold
Current Signal Transduction Therapy Epigenetic Modification in Macrophages: A Promising Target for Tumor and Inflammation-associated Disease Therapy
Current Topics in Medicinal Chemistry Sera/Organ Lysates of Selected Animals Living in Polluted Environments Exhibit Cytotoxicity against Cancer Cell Lines
Anti-Cancer Agents in Medicinal Chemistry miRNAs in Gastrointestinal and Liver Cancers: Their Perspectives and Clinical Applications
Current Pharmaceutical Design Polymeric Nanoparticles of Aromatase Inhibitors: A Comprehensive Review
Current Pharmaceutical Design Chemoprevention with Phytonutrients and Microalgae Products in Chronic Inflammation and Colon Cancer
Current Pharmaceutical Design From Presenilinase to γ-Secretase, Cleave to Capacitate
Current Alzheimer Research MicroRNA-372-3p Predicts Response of TACE Patients Treated with Doxorubicin and Enhances Chemosensitivity in Hepatocellular Carcinoma
Anti-Cancer Agents in Medicinal Chemistry Tumour Hypoxia and Technetium Tracers: In Vivo Studies
Current Radiopharmaceuticals Targeted Therapies in Head and Neck Cancer: Past, Present and Future
Reviews on Recent Clinical Trials miR-203 Suppresses the Proliferation and Metastasis of Hepatocellular Carcinoma by Targeting Oncogene ADAM9 and Oncogenic Long Non-coding RNA HULC
Anti-Cancer Agents in Medicinal Chemistry Aurora-B Kinase Inhibitors for Cancer Chemotherapy
Mini-Reviews in Medicinal Chemistry VEGF Signaling in Cancer Treatment
Current Pharmaceutical Design Targeting Ovarian Cancer-Initiating Cells
Anti-Cancer Agents in Medicinal Chemistry The Possible Involvement of Glycogen Synthase Kinase-3 (GSK-3) in Diabetes, Cancer and Central Nervous System Diseases
Current Pharmaceutical Design Polyphenolic Coumpounds in Chemoprevention of Colon Cancer - Targets and Signaling Pathways
Anti-Cancer Agents in Medicinal Chemistry Applicability and Approaches of (Meth) Acrylate Copolymers (Eudragits) in Novel Drug Delivery Systems
Current Drug Therapy