Abstract
Sucrose hydrolytic enzymes, widely used in a variety of food industries, employ sucrose as a substrate. In addition to their hydrolysis activities, they have other recently discovered characteristics that should make them useful for medical applications. Here, the two enzymes sucrose phosphorylase and invertase are discussed. Sucrose phosphorylase glycosylates non-carbohydrate small molecules and invertase can be used in a portable and personal biosensor to quantify a variety of analytical targets.
Keywords: Sucrose phosphorylase, Invertase, transglycosylation, non-carbohydrate transglycosylation, Biosensor, glucose meter.
Current Topics in Medicinal Chemistry
Title:Sucrose Hydrolytic Enzymes: Old Enzymes for New Uses as Biocatalysts for Medical Applications
Volume: 13 Issue: 10
Author(s): Hao Pang, Liqin Du, Jianxin Pei, YuTuo Wei, Qishi Du and Ribo Huang
Affiliation:
Keywords: Sucrose phosphorylase, Invertase, transglycosylation, non-carbohydrate transglycosylation, Biosensor, glucose meter.
Abstract: Sucrose hydrolytic enzymes, widely used in a variety of food industries, employ sucrose as a substrate. In addition to their hydrolysis activities, they have other recently discovered characteristics that should make them useful for medical applications. Here, the two enzymes sucrose phosphorylase and invertase are discussed. Sucrose phosphorylase glycosylates non-carbohydrate small molecules and invertase can be used in a portable and personal biosensor to quantify a variety of analytical targets.
Export Options
About this article
Cite this article as:
Pang Hao, Du Liqin, Pei Jianxin, Wei YuTuo, Du Qishi and Huang Ribo, Sucrose Hydrolytic Enzymes: Old Enzymes for New Uses as Biocatalysts for Medical Applications, Current Topics in Medicinal Chemistry 2013; 13 (10) . https://dx.doi.org/10.2174/15680266113139990010
DOI https://dx.doi.org/10.2174/15680266113139990010 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Small-molecule Inhibitors of Epigenetic Mutations as Compelling Drugtargets for Myelodysplastic Syndromes
Current Cancer Drug Targets <sup>89</sup>Zr-PET Radiochemistry in the Development and Application of Therapeutic Monoclonal Antibodies and Other Biologicals
Current Topics in Medicinal Chemistry Molecular Profiles of Sentinel and Non-Sentinel Lymph Nodes in Breast Cancer Progression and Prognosis
Current Cancer Therapy Reviews The Vitamin D Saga: Breaking Dawn
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Target Therapies in Pancreatic Carcinoma
Current Medicinal Chemistry Applying Epigenetics to Alzheimer’s Disease via the Latent Early–life Associated Regulation (LEARn) Model
Current Alzheimer Research Nanoparticle-Based Tumor Theranostics with Molecular Imaging
Current Pharmaceutical Biotechnology Pharmacogenetic Syndrome of Dihydropyrimidine Dehydrogenase Deficiency
Current Pharmacogenomics VEGF Signal System: The Application of Antiangiogenesis
Current Medicinal Chemistry Sorafenib (BAY 43-9006) in Hepatocellular Carcinoma Patients: From Discovery to Clinical Development
Current Medicinal Chemistry Sonic Hedgehog Pathway as a Target for Therapy in Angiogenesis-Related Diseases
Current Signal Transduction Therapy MRI of the Small and Large Bowel
Current Medical Imaging The Potential Role of Pharmacogenomic and Genomic in the Adjuvant Treatment of Early Stage Non Small Cell Lung Cancer
Current Genomics Olive Oil and Apoptosis of Cancer Cells
Current Nutrition & Food Science Preface:
Current Topics in Medicinal Chemistry Selected Attributes of Polyphenols in Targeting Oxidative Stress in Cancer
Current Topics in Medicinal Chemistry Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3
CNS & Neurological Disorders - Drug Targets Nampt/Visfatin/PBEF: A Functionally Multi-faceted Protein with a Pivotal Role in Malignant Tumors
Current Pharmaceutical Design Viral Vectors for Cancer Gene Therapy: Viral Dissemination and Tumor Targeting
Current Gene Therapy A Review on Multi-organ Cancer Detection Using Advanced Machine Learning Techniques
Current Medical Imaging