Abstract
A variety of chiral bisamide ligands have been prepared and widely used in asymmetric catalytic syntheses with highly regioand enantioselective products, especially in the transition-metal-catalyzed asymmetric allylic alkylation reactions. The achievements in the asymmetric allylic alkylation reactions with various nucleophiles have been reviewed. The applications of some typical chiral bisamides in decarboxylative asymmetric allylic alkylation of enol carbonates, [3+2] cycloaddition of vinyl cyclopropanes and alkylidene azlactones, and aldol reactions are also introduced.
Keywords: Bisamide, ligand, asymmetric catalysis, allylic alkylation, nucleophile.
Current Organic Synthesis
Title:Application of Chiral Bisamide Ligands in Asymmetric Catalytic Syntheses
Volume: 10 Issue: 3
Author(s): Chan Zhou and Jiaxi Xu
Affiliation:
Keywords: Bisamide, ligand, asymmetric catalysis, allylic alkylation, nucleophile.
Abstract: A variety of chiral bisamide ligands have been prepared and widely used in asymmetric catalytic syntheses with highly regioand enantioselective products, especially in the transition-metal-catalyzed asymmetric allylic alkylation reactions. The achievements in the asymmetric allylic alkylation reactions with various nucleophiles have been reviewed. The applications of some typical chiral bisamides in decarboxylative asymmetric allylic alkylation of enol carbonates, [3+2] cycloaddition of vinyl cyclopropanes and alkylidene azlactones, and aldol reactions are also introduced.
Export Options
About this article
Cite this article as:
Zhou Chan and Xu Jiaxi, Application of Chiral Bisamide Ligands in Asymmetric Catalytic Syntheses, Current Organic Synthesis 2013; 10 (3) . https://dx.doi.org/10.2174/1570179411310030005
DOI https://dx.doi.org/10.2174/1570179411310030005 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Meta Analysis of Advanced Cancer Survival Data Using Lognormal Parametric Fitting: A Statistical Method to Identify Effective Treatment Protocols
Current Pharmaceutical Design The Role of Atomic Spectrometric Techniques in the Determination of Chemical Elements in Atmospheric Aerosols
Current Analytical Chemistry A Tour of Unsupervised Deep Learning for Medical Image Analysis
Current Medical Imaging Cutaneous Metabolism in Transdermal Drug Delivery
Current Drug Metabolism Recent Advances in Porphyrin-Derived Sensors
Current Organic Chemistry Progress in Developing Amphiphilic Cyclodextrin-Based Nanodevices for Drug Delivery
Current Topics in Medicinal Chemistry Targeting Inhibition of COX-2: A Review of Patents, 2002 - 2006
Recent Patents on Inflammation & Allergy Drug Discovery Amniotic Fluid Stem Cells: a Promising Therapeutic Resource for Cell-Based Regenerative Therapy
Current Pharmaceutical Design Small-molecule Antiviral Agents in Ongoing Clinical Trials for COVID-19
Current Drug Targets Cervical Cancer Diagnosis: Insights into Biochemical Biomarkers and Imaging Techniques
Combinatorial Chemistry & High Throughput Screening The Plasma Levels of hsa-miR-19b-3p, hsa-miR-125b-5p, and hsamiR- 320c in Patients with Asthma, COPD and Asthma-COPD Overlap Syndrome (ACOS)
MicroRNA Safety and Quality of Nutraceuticals: Have FSSAI Guidelines been Able to Blaze the Trail?
Applied Clinical Research, Clinical Trials and Regulatory Affairs Synthesis, Reactions and Biological Evaluation of 3-Amino-6- (subs.)thieno[2,3-b]pyridine-2-carbohydrazides
Current Bioactive Compounds Membrane Domains and the “Lipid Raft” Concept
Current Medicinal Chemistry Recent Advances in Medicinal Applications of Coinage-Metal (Cu and Ag) N-Heterocyclic Carbene Complexes
Current Topics in Medicinal Chemistry Bioinformatics Tools for Mass Spectrometry-Based High-Throughput Quantitative Proteomics Platforms
Current Proteomics Self-Assembly Drugs: From Micelles to Nanomedicine
Current Topics in Medicinal Chemistry Synthesis and Evaluation of N-Benzyl-Acridinone Derivatives Induced Apoptosis in Human Liver Cancer Cell-Lines
Letters in Drug Design & Discovery Evaluation of the Effects of 1,25 Vitamin D3 on Regulatory T Cells and T Helper 17 Cells in Vitamin D-deficient Women with Unexplained Recurrent Pregnancy Loss
Current Molecular Pharmacology Advances in the Treatment of Neurodegenerative Disorders Employing Nanoparticles
Recent Patents on Drug Delivery & Formulation