Abstract
Food allergies, defined as an immune response to food proteins, affect as many as 8% of young children and 2% of adults in westernized countries, and their prevalence appears to be rising like all allergic diseases. In addition to well-recognized urticaria and anaphylaxis triggered by IgE antibody–mediated immune responses, there is an increasing recognition of cell-mediated disorders such as eosinophilic esophagitis and food protein–induced enterocolitis. New knowledge is being developed on the pathogenesis of both IgE and non-IgE mediated disease. Currently, management of food allergies consists of educating the patient to avoid ingesting the responsible allergen and initiating therapy if ingestion occurs. However, novel strategies are being studied, including sublingual/oral immunotherapy and others with a hope for the future.
Keywords: Food Allergy, IgE, non-IgE.
Current Pharmaceutical Design
Title:Food Allergy
Volume: 20 Issue: 6
Author(s): Antonella Cianferoni
Affiliation:
Keywords: Food Allergy, IgE, non-IgE.
Abstract: Food allergies, defined as an immune response to food proteins, affect as many as 8% of young children and 2% of adults in westernized countries, and their prevalence appears to be rising like all allergic diseases. In addition to well-recognized urticaria and anaphylaxis triggered by IgE antibody–mediated immune responses, there is an increasing recognition of cell-mediated disorders such as eosinophilic esophagitis and food protein–induced enterocolitis. New knowledge is being developed on the pathogenesis of both IgE and non-IgE mediated disease. Currently, management of food allergies consists of educating the patient to avoid ingesting the responsible allergen and initiating therapy if ingestion occurs. However, novel strategies are being studied, including sublingual/oral immunotherapy and others with a hope for the future.
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Cite this article as:
Cianferoni Antonella, Food Allergy, Current Pharmaceutical Design 2014; 20 (6) . https://dx.doi.org/10.2174/13816128113199990044
DOI https://dx.doi.org/10.2174/13816128113199990044 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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