Abstract
Twelve 4-arylmethylidene-2-phenyl-4H-oxazol-5-ones were prepared in excellent yield by sonicating a mixture of an araldehyde, hippuric acid and acetic anhydride in the presence of a green heterogeneous NanoMgO as a basic catalyst. The catalytic activity of NanoMgO was found to be higher compared with bulk MgO powder under the same conditions. This method provides several advantages such as short reaction time, high yields, cleaner reaction condition, involves simple and easy workup procedure makes this protocol economically viable.
Keywords: 4-Arylmethylidene-2-phenyl-4H-oxazol-5-ones, Nano-MgO, hippuric acid, aromatic aldehydes, acetic anhydride, Ultrasonic-irradiation.
Letters in Organic Chemistry
Title:Sonochemical Hot-spot Assisted One-pot Synthesis of 4-arylmethylidene - 2-phenyl-4H-oxazol-5-ones Using Nano-MgO as an Efficient Catalyst
Volume: 10 Issue: 4
Author(s): Sadeq Hamood Saleh Azzam, G. T. Chandrappa and Mohamed Afzal Pasha
Affiliation:
Keywords: 4-Arylmethylidene-2-phenyl-4H-oxazol-5-ones, Nano-MgO, hippuric acid, aromatic aldehydes, acetic anhydride, Ultrasonic-irradiation.
Abstract: Twelve 4-arylmethylidene-2-phenyl-4H-oxazol-5-ones were prepared in excellent yield by sonicating a mixture of an araldehyde, hippuric acid and acetic anhydride in the presence of a green heterogeneous NanoMgO as a basic catalyst. The catalytic activity of NanoMgO was found to be higher compared with bulk MgO powder under the same conditions. This method provides several advantages such as short reaction time, high yields, cleaner reaction condition, involves simple and easy workup procedure makes this protocol economically viable.
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Cite this article as:
Hamood Saleh Azzam Sadeq, Chandrappa G. T. and Afzal Pasha Mohamed, Sonochemical Hot-spot Assisted One-pot Synthesis of 4-arylmethylidene - 2-phenyl-4H-oxazol-5-ones Using Nano-MgO as an Efficient Catalyst, Letters in Organic Chemistry 2013; 10 (4) . https://dx.doi.org/10.2174/1570178611310040010
DOI https://dx.doi.org/10.2174/1570178611310040010 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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