Abstract
Fourteen novel compounds were obtained and their chemical structures were established by 1H-NMR and IR spectra as well as elemental analyses. As one of the most important factors determining the changes of activity of respective fluorophenyl and iodophenyl derivatives, one should consider the volume of halogen substituent and its influence on the lipophilicity of the entire molecule.
Keywords: Aminomethylation, Drug-resistance, Hydroxymethylation, s-triazoles, 1, 2, 4-triazole derivatives, N2-aminomethyl/hydroxymethyl derivative, N4-aryl moiety, Staphylococcus aureus, Elemental analyses, N4-(4-fluorophenyl)
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