Abstract
Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.
Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor
Current Medicinal Chemistry
Title:Dendrimers in Photodynamic Therapy
Volume: 19 Issue: 29
Author(s): B. Klajnert, M. Rozanek and M. Bryszewska
Affiliation:
Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor
Abstract: Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.
Export Options
About this article
Cite this article as:
Klajnert B., Rozanek M. and Bryszewska M., Dendrimers in Photodynamic Therapy, Current Medicinal Chemistry 2012; 19 (29) . https://dx.doi.org/10.2174/0929867311209024903
DOI https://dx.doi.org/10.2174/0929867311209024903 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Prospective Function of Different Antioxidant Containing Natural Products in the Treatment of Neurodegenerative Diseases
CNS & Neurological Disorders - Drug Targets Radionuclide Liver Cancer Therapies: From Concept to Current Clinical Status
Anti-Cancer Agents in Medicinal Chemistry Super Water-Repellent Surfaces: Potential Application to Drag Reduction of Yachts
Recent Patents on Materials Science Gene Therapy for Parkinsons and Alzheimers Diseases: from the Bench to Clinical Trials
Current Pharmaceutical Design Macroautophagy as a Target of Cancer Therapy
Current Cancer Therapy Reviews Thirty Years of Polyamine-Related Approaches to Cancer Therapy. Retrospect and Prospect. Part 2. Structural Analogues and Derivatives
Current Drug Targets Structure-Function Relationships in the Interaction Between the Urokinase- Type Plasminogen Activator and Its Receptor
Current Pharmaceutical Design Cell Cycle and Cancer: The G1 Restriction Point and the G1 / S Transition
Current Genomics The Macrophage Stimulating Protein/Ron Pathway as a Potential Therapeutic Target to Impede Multiple Mechanisms Involved in Breast Cancer Progression
Current Drug Targets Cell-Penetrating Peptide-Mediated Therapeutic Molecule Delivery into the Central Nervous System
Current Neuropharmacology Imaging Drug Resistance with Radiolabeled Molecules
Current Pharmaceutical Design A Novel Polyarginine Containing Smac Peptide Conjugate that Mediates Cell Death in Tumor and Healthy Cells
Medicinal Chemistry Melatonin in the Biliary Tract and Liver: Health Implications
Current Pharmaceutical Design microRNA as Biomarkers and Regulator of Cardiovascular Development and Disease
Current Pharmaceutical Design Radiolabeled Probes Targeting G-Protein-Coupled Receptors for Personalized Medicine
Current Pharmaceutical Design HLA-G - From Fetal Tolerance to a Regulatory Molecule in Inflammatory Diseases
Current Immunology Reviews (Discontinued) Role of Prolyl Endopeptidase in Intracellular Transport and Protein Secretion
CNS & Neurological Disorders - Drug Targets Effect of PUFAs Oral Administration on the Amount of Apoptotic Caspases Enzymes in Gastric Cancer Patients Undergoing Chemotherapy
Anti-Cancer Agents in Medicinal Chemistry Synergistic Effect of α-Solanine and Cisplatin Induces Apoptosis and Enhances Cell Cycle Arrest in Human Hepatocellular Carcinoma Cells
Anti-Cancer Agents in Medicinal Chemistry Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry