Abstract
Food bioactives represent diet based molecules that perform physiological roles related to disease prevention and/or treatment. As such considerable overlap exists between food bioactives and drugs, the purpose of this overview is to present the case for comparing and contrasting foods versus drugs in several models of health and disease, some of which are presented in further detail in subsequent chapters of this miniseries. The present review concludes that in some instances distinction is difficult between metabolic processes influenced by foods versus drugs and that the two types of compounds exerts overlapping or identical actions in prevention and treatment of disease. In summary, there appears to be evidence of a role for functional foods in disease treatment, thus we need to look at a paradigm shift to decrease the dependency on drugs and increase the use of food based materials for therapeutic use. Over the longer term, functional foods and nutraceuticals must find ways to compete with pharmaceuticals on an even playing field.
Keywords: Bioprocesses, drugs, food bioactives, metabolic actions, synergism
Current Pediatric Reviews
Title:Food Bioactives versus Drugs – Introduction
Volume: 8 Issue: 3
Author(s): Emanuel Lebenthal and Peter J.H. Jones
Affiliation:
Keywords: Bioprocesses, drugs, food bioactives, metabolic actions, synergism
Abstract: Food bioactives represent diet based molecules that perform physiological roles related to disease prevention and/or treatment. As such considerable overlap exists between food bioactives and drugs, the purpose of this overview is to present the case for comparing and contrasting foods versus drugs in several models of health and disease, some of which are presented in further detail in subsequent chapters of this miniseries. The present review concludes that in some instances distinction is difficult between metabolic processes influenced by foods versus drugs and that the two types of compounds exerts overlapping or identical actions in prevention and treatment of disease. In summary, there appears to be evidence of a role for functional foods in disease treatment, thus we need to look at a paradigm shift to decrease the dependency on drugs and increase the use of food based materials for therapeutic use. Over the longer term, functional foods and nutraceuticals must find ways to compete with pharmaceuticals on an even playing field.
Export Options
About this article
Cite this article as:
Lebenthal Emanuel and J.H. Jones Peter, Food Bioactives versus Drugs – Introduction, Current Pediatric Reviews 2012; 8 (3) . https://dx.doi.org/10.2174/157339612802139451
DOI https://dx.doi.org/10.2174/157339612802139451 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Editorial (Thematic Issue: Disease Control and Active and Healthy Ageing: New Paradigms of Therapeutic Strategy)
Current Pharmaceutical Design Targeting Angiogenesis in Ovarian Carcinoma
Current Cancer Therapy Reviews Estimated Arterial Stiffness and Prediction of Vascular Aging: The Rising of a New Era
Current Pharmaceutical Design Editorial [Hot Topic: Current Hypertension Reviews: Hot Topics Hypertension and Diabetes: An Emphasis on the RAS (Guest Editors: Karin A.M. Jandeleit-Dahm and Terri J. Allen)]
Current Hypertension Reviews Isolation and Biological Evaluation of Novel Tetracosahexaene Hexamethyl, an Acyclic Triterpenoids Derivatives and Antioxidant from Justicia adhatoda
Combinatorial Chemistry & High Throughput Screening Interaction Between Platelets and Cytokines - A Possible Role in the Pathogenesis of Preeclampsia
Vascular Disease Prevention (Discontinued) Dynamics of Diabetes and Obesity: An Alarming Situation in the Developing Countries in Asia
Mini-Reviews in Medicinal Chemistry Editorial (Thematic Issue: Epigenetic Modulations in Kidney Podocytes: A Possible Target of Treatment for Proteinuria)
Current Hypertension Reviews Role of COL4A1 in Basement-Membrane Integrity and Cerebral Small-Vessel Disease. The COL4A1 Stroke Syndrome
Current Medicinal Chemistry Transposable Elements in Cancer and Other Human Diseases
Current Cancer Drug Targets Use of BNP and CRP as Biomarkers in Assessing Cardiovascular Disease:Diagnosis Versus Risk
Current Vascular Pharmacology Women Tipping the Scale During Pregnancy: A Special Population for Obesity Interventions,Treatments and Clinical Trials
Current Pharmaceutical Design Recent Advances on Nitric Oxide in the Upper Airways
Current Medicinal Chemistry Gestational Programming of Offspring Obesity: A Potential Contributor to Alzheimers Disease
Current Alzheimer Research Fatty Acids: Friends or Foe? Relation Between Dietary Fat and Insulin Sensitivity
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) New Perspectives on Acetaminophen
Current Cardiology Reviews Hydroxamic Acids as Pharmacological Agents
Current Medicinal Chemistry Social Determinants of Childhood Obesity: Beyond Individual Choices
Current Pediatric Reviews Impact of Nutrition Transition and Resulting Morbidities on Economic and Human Development
Current Diabetes Reviews Editorial (Thematic Issue: Cardio-Metabolic Complications: Current Perspective and Future Developments)
Current Pharmaceutical Design