Contribution of Dietary Factors to Peroxisome Proliferator-Activated Receptor-Mediated Inflammatory Signaling in Arthritic Diseases

Title:Contribution of Dietary Factors to Peroxisome Proliferator-Activated Receptor-Mediated Inflammatory Signaling in Arthritic Diseases

Volume: 8 Issue: 2

Author(s): Kayo Masuko

Affiliation:

Keywords: Arthritis, diet, nutrient, PPARs, review.

Abstract: Diet-derived natural ligands of the peroxisome proliferator-activated receptor (PPAR) family of nuclear receptors have been widely reported to activate PPAR signaling, modifying gene and protein expressions in a variety of cells and tissues. Examples of such dietary factors include unsaturated fatty acids, spices, soy protein, and polyphenols. Recent data suggest that these nutrients may affect inflammation and immunity in arthritic diseases. This review describes these nutrients and their potential modulating effects on the pathophysiology of inflammatory and degenerative arthritis through PPAR signaling.

Cite this article as:

Masuko Kayo, Contribution of Dietary Factors to Peroxisome Proliferator-Activated Receptor-Mediated Inflammatory Signaling in Arthritic Diseases, Current Rheumatology Reviews 2012; 8 (2) . https://dx.doi.org/10.2174/157339712802083803

DOI https://dx.doi.org/10.2174/157339712802083803	Print ISSN 1573-3971
Publisher Name Bentham Science Publisher	Online ISSN 1875-6360