A Dialogue about Protein Crystallization and Phase Diagrams

Neer      Asherie

doi:10.2174/092986612800793217

Abstract

A lighthearted researcher and a disheartened student discuss the challenges of protein crystallization and how phase diagrams can be used to address these challenges. The student feels a little better afterwards, but many proteins remain uncrystallized.

Keywords: Crystal nucleation, growth, protein crystallization , impurities, solubility curve, solubility limit, crystallization agent, crystallization robot, thermodynamically stable, precipitation