Subclinical Hypothyroidism and Homeostatic Disturbances: Case Report and Literature Review

Parvaneh      Ehsanzadeh-Cheemeh; Michelle      Thompson; Michal      Miller

doi:10.2174/187221412800604590

Abstract

Abnormalities of coagulation have been reported in patients with thyroid dysfunction, although there is no clear information to explain the mechanism behind such irregularities. We are presenting a case of subclinical hypothyroidism that came with coagulation disturbance (hypocoagulation). Her symptoms resolved with leothyroxin in 4 weeks. Further studies are needed to clear the pathogenesis of the coagulation disturbance in such setting. The article also outlines some patents on hypothyroidism and hyperthyroidism.

Keywords: Hemostasis, hypercoagulability hypocoagulability, subclinical thyroid dysfunction, thyroid dysfunction, hypothyroidism, Graves’ disease, vitamin-mineral complexes, levothyroxine, Willebrand factor