NaOH-Al2O3 Catalyzed Synthesis of 1, 3, 5-triarylpentane-1, 5-diones Derivatives Under Solvent-Free Condition and Crystal Structure of 3-(2’, 4’-dichlorophenyl)-1, 5-diphenylpentane-1, 5-dione

Title:NaOH-Al2O3 Catalyzed Synthesis of 1, 3, 5-triarylpentane-1, 5-diones Derivatives Under Solvent-Free Condition and Crystal Structure of 3-(2’, 4’-dichlorophenyl)-1, 5-diphenylpentane-1, 5-dione

Volume: 9 Issue: 4

Author(s): Xianqiang Huang, Qiu Feng, Yanliang Sun, Qingpeng He, Yong Wang

Affiliation:

Keywords: 3, 5-triarylpentane-1, NaOH/Al2O3, crystal structure, 5-diones, Green Chemistry, cyclohexenones, pyridines, multi-substituted cyclodipentanes, heterocyclic compounds, triarylpentane-1, 5-dione

Abstract: An efficient procedure for rapidly synthesizing the 1,3,5-triarylpentane-1,5-diones compounds using aromatic aldehydes and aromatic ketones as starting materials by tandem aldol reactions/Michael additions under NaOH/Al2O3 and the solvent-free conditions has been described. All compounds were characterized by IR, 1H NMR and elemental analysis. Additionally, the crystal structure of 3-(2’,4’-dichlorophenyl)-1,5-diphenylpentane-1,5-dione was obtained and determined by X-ray single-crystal diffraction. The protocol offers several advantages such as a simple, eco-friendly procedure and mild reaction conditions.

Cite this article as:

Xianqiang Huang, Qiu Feng, Yanliang Sun, Qingpeng He, Yong Wang , NaOH-Al2O3 Catalyzed Synthesis of 1, 3, 5-triarylpentane-1, 5-diones Derivatives Under Solvent-Free Condition and Crystal Structure of 3-(2’, 4’-dichlorophenyl)-1, 5-diphenylpentane-1, 5-dione, Letters in Organic Chemistry 2012; 9 (4) . https://dx.doi.org/10.2174/157017812800233732