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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of Mycinose from 1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose

Author(s): Kai Bao, Hao Gao, Zhibin Zhu, Jinhong Wang, Guoning Zhang, Jun Sun, Weige Zhang and Xinsheng Yao

Volume 8, Issue 8, 2011

Page: [592 - 595] Pages: 4

DOI: 10.2174/157017811797249290

Price: $65

Abstract

A facile synthesis of mycinose from commercially available 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose was developed. A selective and direct reductive debromination of α-hydroxy bromides in a simple NaBH4/EtOH/H2O system was found.

Keywords: 1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose, debromination, mycinose, synthesis, glucofuranose, stoichiometry, hydroxyl group, Microwave assisted deprotection, spectroscopy, sodium borohydride


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