One-Pot Preparation of N,N'-Alkylidene Bisamide Derivatives Catalyzed by Silica Supported Magnesium Chloride (SiO2-MgCl2)

Title: One-Pot Preparation of N,N'-Alkylidene Bisamide Derivatives Catalyzed by Silica Supported Magnesium Chloride (SiO2-MgCl2)

Volume: 8 Issue: 8

Author(s): Mohammad R.M. Shafiee

Affiliation:

Keywords: Amide, Heterogeneous catalyst, N, N'-alkylidene bisamide, Silica Supported Magnesium Chloride (SiO2-MgCl2), aldehydes, alkyne, purification, pharmacological, oxazine, bisamides

Abstract: A highly efficient and simple procedure for the preparation of N,N'-alkylidene bisamides via one-pot threecomponent condensation reaction of phenyl acetylene/1-Hexyne, aromatic aldehyde and benzamide/acetamide in the presence of catalytic amount of silica supported magnesium chloride (SiO2-MgCl2) under thermal solvent-free conditions is described. All of the reactions proceeded in high yields and in relatively short reaction times.

Cite this article as:

R.M. Shafiee Mohammad, One-Pot Preparation of N,N'-Alkylidene Bisamide Derivatives Catalyzed by Silica Supported Magnesium Chloride (SiO2-MgCl2), Letters in Organic Chemistry 2011; 8 (8) . https://dx.doi.org/10.2174/157017811797249344