An Efficient One Pot Synthesis of New Indanopyrazoline and Indanopyrazole Derivatives

Title: An Efficient One Pot Synthesis of New Indanopyrazoline and Indanopyrazole Derivatives

Volume: 8 Issue: 4

Author(s): Hanene Jelizi, Mohamed M. Rammah, Moheddine Askri, Mohamed El Baker Rammah, Kabula Ciamala and Karin Monnier-Jobe

Affiliation:

Keywords: 1-Aminoindenes, C-aryl-N-phenylnitrilimines, [3+2] Cycloaddition, pyrazole, pyrazoline, regiochemistry, diazoalkanes, diarylnitrilimines, heteroaromatization, dipolarophile

Abstract: Synthesis of a series of novel fused pyrazolines and pyrazoles has been accomplished in good yields by regio- and diastereoselective 1,3-dipolar cycloaddition of enamines of indan-1-one 1a-c towards C-aryl-N-phenylnitrilimines 2df. The structure of the cycloadducts was elucidated by 1D and 2D NMR studies.

Cite this article as:

Jelizi Hanene, M. Rammah Mohamed, Askri Moheddine, El Baker Rammah Mohamed, Ciamala Kabula and Monnier-Jobe Karin, An Efficient One Pot Synthesis of New Indanopyrazoline and Indanopyrazole Derivatives, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371421