An Improved Process for the Production of Rivastigmine Tartrate, a Cholinesterase Inhibitor

Title: An Improved Process for the Production of Rivastigmine Tartrate, a Cholinesterase Inhibitor

Volume: 7 Issue: 2

Author(s): Vajrala Venkata Reddy, Mandava Venkata Naga Brahmeswara Rao, Varanasi Ganesh, Adla Vijaya Kumar, Cherukupally Praveen, Khagga Mukkanti, Ganta Mahesh Reddy and Ganta Madhusudhan Reddy

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Keywords: Rivastigmine tartrate, a cholinesterase inhibitor, alzheimer's disease, improved process, impurities

Abstract: An improved and scalable process for the production of rivastigmine tartrate is reported. The improved process provides rivastigmine tartrate at considerably lower cost and allows the omission of hazardous chemicals. The overall yield is increased from 4.66% (reported process) to 17% with the improved process.

Cite this article as:

Reddy Venkata Vajrala, Naga Brahmeswara Rao Venkata Mandava, Ganesh Varanasi, Kumar Vijaya Adla, Praveen Cherukupally, Mukkanti Khagga, Reddy Mahesh Ganta and Reddy Madhusudhan Ganta, An Improved Process for the Production of Rivastigmine Tartrate, a Cholinesterase Inhibitor, Letters in Organic Chemistry 2010; 7 (2) . https://dx.doi.org/10.2174/157017810790796246