Abstract
Previous to the availability of antimicrobial therapy, infective endocarditis (IE) was habitually lethal. Although approximately 80 percent of patients with endocarditis currently survive their infections, one of every six patients with IE does not survive the initial hospitalization, and up to one-third of patients infected with highly virulent organisms (such as Staphylococcus aureus) may die as a direct or indirect result of their valvular infection. An unfavourable outcome in these patients can occur despite having received appropriate antimicrobial therapy in a suitable approach, and despite the expert use of modern diagnostic techniques. Our purpose is to review the main issues related to the antimicrobial therapy.
Keywords: Infective endocarditis, microorganisms, antimicrobial regimens
Infectious Disorders - Drug Targets
Title: Antibiotic Treatment in Native Valve Infective Endocarditis
Volume: 10 Issue: 1
Author(s): Rafael Garcia-Borbolla and Mariano Garcia-Borbolla
Affiliation:
Keywords: Infective endocarditis, microorganisms, antimicrobial regimens
Abstract: Previous to the availability of antimicrobial therapy, infective endocarditis (IE) was habitually lethal. Although approximately 80 percent of patients with endocarditis currently survive their infections, one of every six patients with IE does not survive the initial hospitalization, and up to one-third of patients infected with highly virulent organisms (such as Staphylococcus aureus) may die as a direct or indirect result of their valvular infection. An unfavourable outcome in these patients can occur despite having received appropriate antimicrobial therapy in a suitable approach, and despite the expert use of modern diagnostic techniques. Our purpose is to review the main issues related to the antimicrobial therapy.
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Cite this article as:
Garcia-Borbolla Rafael and Garcia-Borbolla Mariano, Antibiotic Treatment in Native Valve Infective Endocarditis, Infectious Disorders - Drug Targets 2010; 10 (1) . https://dx.doi.org/10.2174/187152610790410927
DOI https://dx.doi.org/10.2174/187152610790410927 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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