Abstract
The synthesis of 1,3-diphenyl-5-arylpyrazoles via the reactions of 2,3-epoxy-1-phenyl-3-aryl-1-propanones with phenylhydrazine was carried out in 48-84% yields at 230 °C under solvent-free condition within 1.5 h. This method provides several advantages such as operational simplicity, higher yield and solvent-free.
Keywords: cyclization, 1,3-diphenyl-5-arylpyrazole, synthesis, solvent-free reaction, heterocycles
Letters in Organic Chemistry
Title: Solvent-Free Synthesis of 1,3-Diphenyl-5-arylpyrazole Derivatives
Volume: 6 Issue: 5
Author(s): Ji-Tai Li, Ying Yin and Xian-Tao Meng
Affiliation:
Keywords: cyclization, 1,3-diphenyl-5-arylpyrazole, synthesis, solvent-free reaction, heterocycles
Abstract: The synthesis of 1,3-diphenyl-5-arylpyrazoles via the reactions of 2,3-epoxy-1-phenyl-3-aryl-1-propanones with phenylhydrazine was carried out in 48-84% yields at 230 °C under solvent-free condition within 1.5 h. This method provides several advantages such as operational simplicity, higher yield and solvent-free.
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Cite this article as:
Li Ji-Tai, Yin Ying and Meng Xian-Tao, Solvent-Free Synthesis of 1,3-Diphenyl-5-arylpyrazole Derivatives, Letters in Organic Chemistry 2009; 6 (5) . https://dx.doi.org/10.2174/157017809788681383
DOI https://dx.doi.org/10.2174/157017809788681383 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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