Abstract
Reaction of polymer-supported selenium bromide with ortho allylated phenols and subsequent cleavage from the polymer by treatment of methyl iodide efficiently afforded 2-iodomethyl-2,3-dihydrobenzofurans in good yields and high purities. The polymeric reagent can be regenerated and reused as environmentally friendly reagent.
Keywords: Solid-phase organic synthesis, Polymer-supported selenium bromide, Recyclable, Selenium mediated intramolecular cyclization, 2-Iodomethyl-2,3-dihydrobenzofuran, Traceless cleavage
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