A Novel Biginelli-Like Reaction: An Efficient One-pot Synthesis of Spiro[oxindole-quinazoline/pyrimidine]ones

Title: A Novel Biginelli-Like Reaction: An Efficient One-pot Synthesis of Spiro[oxindole-quinazoline/pyrimidine]ones

Volume: 7 Issue: 4

Author(s): Hassan Kefayati, Kurosh Rad-Moghadam, Masoumeh Zamani and Sanaz Hosseyni

Affiliation:

Keywords: Quinazolinone, pyrimidinone, spiro oxindole, multi-component reaction, Biginelli-like reaction, isatin

Abstract: Some new spiro[oxindole-quinazoline/pyrimidine]ones were synthesized via a novel three-component Biginelli-like reaction between isatin, cyclic or acyclic 1,3-dicarbonyl compounds, and urea, N-methyl urea or thiourea in one pot and good yields.

Cite this article as:

Kefayati Hassan, Rad-Moghadam Kurosh, Zamani Masoumeh and Hosseyni Sanaz, A Novel Biginelli-Like Reaction: An Efficient One-pot Synthesis of Spiro[oxindole-quinazoline/pyrimidine]ones, Letters in Organic Chemistry 2010; 7 (4) . https://dx.doi.org/10.2174/157017810791130577