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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

A Short Route to [1,2,3]-Triazolyl Coumarin and Quinolone Derivatives by Cu(I) Catalyzed 1,3-Dipolar Cycloaddition and Fluorescence Studies

Author(s): Krishna C. Majumdar and Shovan Mondal

Volume 6, Issue 1, 2009

Page: [82 - 87] Pages: 6

DOI: 10.2174/157017809787003250

Price: $65

Abstract

Hitherto unreported [1,2,3]-triazolyl coumarin and quinolone derivatives in good to excellent yields have been expediently synthesized from 6- and 7-azidocoumarin and 6-azidoquinolone by copper (I) catalyzed 1,3-dipolar cycloaddition. Azidocoumarins and azidoquinolones were in turn prepared efficiently from the corresponding amines. Fluorescence studies of the newly synthesized [1,2,3]- triazolyl coumarin and quinolone derivatives are also described.

Keywords: 1,3-dipolar cycloaddition, 6 and 7-azidocoumarin, 6-azidoquinolone, [1,2,3] triazole, phenyl acetylene, fluorescence


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