Abstract
Neurological/neuropsychiatric complications are commonly observed after heart surgery. They include the cerebral ischemic episode, transient ischemic attack, postoperative cognitive decline and postoperative delirium. In this review article, we are dealing with the etiology of these complications, mainly focusing on the role of genetic components. We are also commenting on the putative role of certain pharmacologic agents in the treatment of the aforementioned nosological entities.
Keywords: Genetic polymorphisms, brain injury, heart surgery, risperidone, ondasentron, adamantines, inflammatory response
Recent Patents on CNS Drug Discovery (Discontinued)
Title: Neurolological Disorders and Neuroprotection After Heart Surgery
Volume: 3 Issue: 3
Author(s): Georgios I. Tagarakis
Affiliation:
Keywords: Genetic polymorphisms, brain injury, heart surgery, risperidone, ondasentron, adamantines, inflammatory response
Abstract: Neurological/neuropsychiatric complications are commonly observed after heart surgery. They include the cerebral ischemic episode, transient ischemic attack, postoperative cognitive decline and postoperative delirium. In this review article, we are dealing with the etiology of these complications, mainly focusing on the role of genetic components. We are also commenting on the putative role of certain pharmacologic agents in the treatment of the aforementioned nosological entities.
Export Options
About this article
Cite this article as:
Tagarakis I. Georgios, Neurolological Disorders and Neuroprotection After Heart Surgery, Recent Patents on CNS Drug Discovery (Discontinued) 2008; 3 (3) . https://dx.doi.org/10.2174/157488908786242416
DOI https://dx.doi.org/10.2174/157488908786242416 |
Print ISSN 1574-8898 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3954 |
Related Articles
-
Highlighting the Role of Cognitive and Brain Reserve in the Substance use Disorder Field
Current Neuropharmacology Current Options in the Treatment of Mast Cell Mediator-Related Symptoms in Mastocytosis
Inflammation & Allergy - Drug Targets (Discontinued) Histamine as a Potential Adjuvant to Immuno and Radiotherapy for Cancer Treatment: Discovering New Functions for the Oldest Biogenic Amine
Current Immunology Reviews (Discontinued) Pharmacologic Therapy In Traumatic Brain Injury: Update On Experimental Treatment Strategies
Current Pharmaceutical Design Signaling Pathways Involved in Antidepressant-Induced Cell Proliferation and Synaptic Plasticity
Current Pharmaceutical Design Current Status of Newer Antiinfectives
Recent Patents on Anti-Infective Drug Discovery Beneficial Effects of Herbs, Spices and Medicinal Plants on the Metabolic Syndrome, Brain and Cognitive Function
Central Nervous System Agents in Medicinal Chemistry Azathioprine in Multiple Sclerosis
Mini-Reviews in Medicinal Chemistry The Role of Glial Cells in Drug Abuse
Current Drug Abuse Reviews Raxofelast, (±)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic Acid: A New Antioxidant to Modulate the Inflammatory Response During Ischemia-Reperfusion Injury and Impaired Wound Healing
Mini-Reviews in Medicinal Chemistry Hyperglycemia, Hypoglycemia and Dementia: Role of Mitochondria and Uncoupling Proteins
Current Molecular Medicine Mechanism(s) Involved in Opioid Drug Abuse Modulation of HAND
Current HIV Research Anti-Vascular Endothelial Growth Factor Treatment in Retinal Vein Occlusions
Current Drug Therapy Metabolic Effects of Resveratrol in Mammals - a Link Between Improved Insulin Action and Aging
Current Aging Science Calcium Sensitizers in Cardiac Surgery: Who, When, How and Why?
Current Vascular Pharmacology Bevacizumab and Angiogenesis Inhibitors in the Treatment of CNS Metastases: The Road less Travelled
Current Molecular Pharmacology Synthetic Sphingosine 1-Phosphate Receptor Modulators - Opportunities and Potential Pitfalls
Current Topics in Medicinal Chemistry Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS
Current Neuropharmacology Antidiabetic Potential of Fabaceae Family: An Overview
Current Nutrition & Food Science Synthesis of Novel Benzoquinones with Anti-Inflammatory Activity
Letters in Drug Design & Discovery