An Intriguing, Regioselective Synthesis of Novel 2-(1-Adamantylmethyl) tetrahydropyridines

Title: An Intriguing, Regioselective Synthesis of Novel 2-(1-Adamantylmethyl) tetrahydropyridines

Volume: 5 Issue: 1

Author(s): George B. Foscolos, Ioannis Papanastasiou and Andrew Tsotinis

Affiliation:

Keywords: N-acyl adamantylmethylpiperidines, N-acyl adamantylmethyltetrahydropiperidines, synthesis

Abstract: Treatment of piperidine 8 with acetyl chloride or ethyl chloroformate in the presence of triethylamine gave the 2,3-dehydrogenated products 10a and 10b, respectively, together with the expected N-acylpiperidines 9.

Cite this article as:

Foscolos B. George, Papanastasiou Ioannis and Tsotinis Andrew, An Intriguing, Regioselective Synthesis of Novel 2-(1-Adamantylmethyl) tetrahydropyridines, Letters in Organic Chemistry 2008; 5 (1) . https://dx.doi.org/10.2174/157017808783330117