Syntheses and Biological Activities of Novel N-tert-butyl-N-Alkoxycarbonyl- N-Substituted Benzoylhydrazines and their Derivatives

Title: Syntheses and Biological Activities of Novel N-tert-butyl-N-Alkoxycarbonyl- N-Substituted Benzoylhydrazines and their Derivatives

Volume: 1 Issue: 1

Author(s): Qingmin Wang and Runqiu Huang

Affiliation:

Keywords: alkoxycarbonyl, substitutedbenzoylhydrazines, n-tert-butyl-n-benzoyl- hydrazine, insect growth regulators, anticancer activities

Abstract: A series of novel N-tert-butyl-N-alkoxycarbonyl-N-substitutedbenzoylhydrazines and their derivatives were synthesized. The results of bioassay showed that these title compounds exhibit moderate larvicidal activities, and toxicity assays indicated that these title compounds can induce a premature, abnormal and lethal larval molt. At the same time, we found by chance that these title compounds possess potential anticancer activities in vitro.

Cite this article as:

Wang Qingmin and Huang Runqiu, Syntheses and Biological Activities of Novel N-tert-butyl-N-Alkoxycarbonyl- N-Substituted Benzoylhydrazines and their Derivatives, Letters in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570178043488770