Total Synthesis of the 13,13 Difluoro Analog of the 13 HODE

Title: Total Synthesis of the 13,13 Difluoro Analog of the 13 HODE

Volume: 1 Issue: 1

Author(s): E. Kerouredan, M. Prakesch, D. Gree and R. Gree

Affiliation:

Keywords: fluorine, dast, 13 hode, lipids

Abstract: The first total synthesis of the 13,13 difluoro analog of 13 HODE, via the novel fluorinated synthons (5) and (2), is reported. The key advantages of using a propargylic route for the introduction of the gem difluoro moiety are highlighted below.

Cite this article as:

Kerouredan E., Prakesch M., Gree D. and Gree R., Total Synthesis of the 13,13 Difluoro Analog of the 13 HODE, Letters in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570178043488662