Metal Mediated Dechlorination - A New Route to Nitriles

Title: Metal Mediated Dechlorination - A New Route to Nitriles

Volume: 1 Issue: 1

Author(s): V. K. Tandon and R. B. Chhor

Affiliation:

Keywords: cyclodechlorination, chlorination, nitriles, cyclazines, no donors

Abstract: 1,4-Dichloro-1,4-disubstituted-2,3-diaza-1,3-butadiene 1 undergo cyclodechlorination in presence of Be metal to form cyclazines 3a. Reaction of 1 with Cu, Zn and Mn metals results in formation of nitriles 2. Cyclazines 3 on further oxidation with H2O2 in CH3COOH form NO donors, 1,2-dioxides 4.

Cite this article as:

Tandon K. V. and Chhor B. R., Metal Mediated Dechlorination - A New Route to Nitriles, Letters in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570178043488680