Abstract
The use of targeted toxins in research applications has recently grown considerably. The ability to remove a few specific cells, even when surrounded by different populations, has given scientists a powerful tool for the understanding of systems biology. The use of targeted toxins in research is rich and varied; here we limit ourselves to describe some of those exciting results that researchers have made in the neurosciences.
Keywords: immunotoxin, ligand-toxin, peptide-toxin, saporin, retrograde transport, behavior, molecular surgery, molecular neurosurgery
Mini-Reviews in Medicinal Chemistry
Title: Immunotoxins and Neuropeptide-Toxin Conjugates Experimental Applications
Volume: 4 Issue: 5
Author(s): Dougles A. Lappi and Ronald G. Wiley
Affiliation:
Keywords: immunotoxin, ligand-toxin, peptide-toxin, saporin, retrograde transport, behavior, molecular surgery, molecular neurosurgery
Abstract: The use of targeted toxins in research applications has recently grown considerably. The ability to remove a few specific cells, even when surrounded by different populations, has given scientists a powerful tool for the understanding of systems biology. The use of targeted toxins in research is rich and varied; here we limit ourselves to describe some of those exciting results that researchers have made in the neurosciences.
Export Options
About this article
Cite this article as:
Lappi A. Dougles and Wiley G. Ronald, Immunotoxins and Neuropeptide-Toxin Conjugates Experimental Applications, Mini-Reviews in Medicinal Chemistry 2004; 4 (5) . https://dx.doi.org/10.2174/1389557043403882
DOI https://dx.doi.org/10.2174/1389557043403882 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Brain Targeted Drug Delivery: Factors, Approaches and Patents
Recent Patents on Nanomedicine The Blood-Brain Barrier: Targeting in the Pathogenesis of C. neoformans Meningitis and Drug Discovery
Anti-Infective Agents A Novel Monocyte-based Pyrogen Test Based on the Mechanism of Human Fever Reaction
Current Pharmaceutical Analysis Organic Antifungal Drugs and Targets of Their Action
Current Topics in Medicinal Chemistry The Importance of Precise Documentation of Vaccination by Physicians and Vaccine Providers
Current Drug Safety Central Nervous System Vasculitis: Still More Questions than Answers
Current Neuropharmacology Structure and Functions of Bacterial Outer Membrane Protein A, A Potential Therapeutic Target for Bacterial Infection
Current Topics in Medicinal Chemistry The Multi-faceted Profile of Corticotropin-releasing Factor (CRF) Family of Neuropeptides and of their Receptors on the Paracrine/Local Regulation of the Inflammatory Response
Current Molecular Pharmacology Efficacy and Safety Evaluation of Fixed Dose Combination of Cefepime and Amikacin in Comparison with Cefepime Alone in Treatment of Nosocomial Pneumonia Patients
Current Clinical Pharmacology Enhanced Efficacy of DNA Vaccines Against an Intracellular Bacterial Pathogen by Genetic Adjuvants
Current Pharmaceutical Biotechnology Animal Models in Neurology: Drawbacks and Opportunities
Current Pharmaceutical Design Central Nervous System Manifestations in Systemic Lupus Erythematosus
Current Rheumatology Reviews Temporal Progression of Kainic Acid Induced Changes in Vascular Laminin Expression in Rat Brain with Neuronal and Glial Correlates
Current Neurovascular Research Alzheimers Disease: SPECT and PET Tracers for Beta-Amyloid Imaging
Current Alzheimer Research Efficacy of PD-1 or PD-L1 Inhibitors and Central Nervous System Metastases in Advanced Cancer: A Meta-Analysis
Current Cancer Drug Targets New Development and Application of Ultrasound Targeted Microbubble Destruction in Gene Therapy and Drug Delivery
Current Gene Therapy Invasive Aspergillosis: New Insights into Disease, Diagnostic and Treatment
Current Pharmaceutical Design Recent Advancements in Anti-Migraine Drug Research: Focus on Attempts to Decrease Neuronal Hyperexcitability
Recent Patents on CNS Drug Discovery (Discontinued) Therapeutic Options for the Treatment of 2019-Novel Coronavirus in India: A Review
Coronaviruses Novel AβIsoforms in Alzheimer's Disease - Their Role in Diagnosis and Treatment
Current Pharmaceutical Design