Abstract
A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.
Keywords: ribosome-inactivating proteins, toxins, conjugates, immunotoxins, targeting, immunotherapy
Mini-Reviews in Medicinal Chemistry
Title: Immunotoxins and Other Conjugates: Pre-clinical Studies
Volume: 4 Issue: 5
Author(s): A. Bolognesi and L. Polito
Affiliation:
Keywords: ribosome-inactivating proteins, toxins, conjugates, immunotoxins, targeting, immunotherapy
Abstract: A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.
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Cite this article as:
Bolognesi A. and Polito L., Immunotoxins and Other Conjugates: Pre-clinical Studies, Mini-Reviews in Medicinal Chemistry 2004; 4 (5) . https://dx.doi.org/10.2174/1389557043403864
DOI https://dx.doi.org/10.2174/1389557043403864 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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