Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone

Title: Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone

Volume: 2 Issue: 1

Author(s): Xiao-yu Wu, Xiang-guo Li and Gang Zhao

Affiliation:

Keywords: copper-catalyzed, conjugate-addition, diphenylzinc, phosphine, ligand

Abstract: The copper-catalysed asymmetric conjugate addition of diphenylzinc to 2-cyclohexenone has been carried out with good results. An enantiometric excess of up to 91% was obtained using 5 mol% CuI and 5 mol% phosphine ligand derived from L-proline.

Cite this article as:

Wu Xiao-yu, Li Xiang-guo and Zhao Gang, Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone, Letters in Organic Chemistry 2005; 2 (1) . https://dx.doi.org/10.2174/1570178053400054