Protein Folding Assisted by Chaperones

Title: Protein Folding Assisted by Chaperones

Volume: 12 Issue: 3

Author(s): Julio C. Borges and Carlos H.I. Ramos

Affiliation:

Keywords: molecular chaperones, heat shock proteins, hsp70, chaperonin

Abstract: Molecular chaperones are one of the most important cell defense mechanisms against protein aggregation and misfolding. These specialized proteins bind non-native states of other proteins and assist them in reaching a correctly folded and functional conformation. Chaperones also participate in protein translocation by membranes, in the stabilization of unstable protein conformers and regulatory factors, in the delivery of substrates for proteolysis and in the recovery of proteins from aggregates.

Cite this article as:

Borges C. Julio and Ramos H.I. Carlos, Protein Folding Assisted by Chaperones, Protein & Peptide Letters 2005; 12 (3) . https://dx.doi.org/10.2174/0929866053587165

DOI https://dx.doi.org/10.2174/0929866053587165	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305