Abstract
We report herein the study of the cleavage fragments generated by autoproteolysis of the St. Louis encephalitis virus recombinant protease. The cleavage sites leading to truncated forms were identified by microsequencing, which revealed an unexpected altered specificity of the recombinant proteinase towards unusual sequences.
Keywords: Altered specificity, autoproteolysis, flavivirin, NS3, trypsin-like serine protease