Binding Sites on Laminin Receptors as Components for Antibiotics

Title: Binding Sites on Laminin Receptors as Components for Antibiotics

Volume: 14 Issue: 1

Author(s): Nahoko Kobayashi and Tetsuhiko Yoshida

Affiliation:

Keywords: Laminin, laminin receptor, antimicrobial peptide, minimum inhibitory concentration (MIC), prion, binding site

Abstract: Bacteria use the receptor-adhesion-like interaction between laminin and the laminin receptor in the process of infection. We determined that bacteria do not interact with the receptor-binding site on laminin which could be expected for the bacterial laminin receptor. Rather, binding occurs via the laminin-binding site on the 67-kDa laminin receptor, which has a function similar to the one the bacterial laminin receptor possesses. This finding has implications for the effective use of antimicrobial peptides.

Cite this article as:

Kobayashi Nahoko and Yoshida Tetsuhiko, Binding Sites on Laminin Receptors as Components for Antibiotics, Protein & Peptide Letters 2007; 14 (1) . https://dx.doi.org/10.2174/092986607779117290

DOI https://dx.doi.org/10.2174/092986607779117290	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305