Selective Agents for Serotonin2C (5-HT2C) Receptor

Title: Selective Agents for Serotonin2C (5-HT2C) Receptor

Volume: 6 Issue: 18

Author(s): Enza Lacivita and Marcello Leopoldo

Affiliation:

Keywords: CYP1A2, mCPP, RO600175, anxiolytic, WAY-629, phenylpiperazine

Abstract: The serotonin2C (5-HT2C) receptor has attracted a lot of attention owing to its role in appetite regulation, depression, obsessive-compulsive disorder (OCD), panic disorders, and substance abuse. This review summarizes nonpatent and patent literature up to November 2005 that deals with the synthesis and characterization of selective 5-HT2C receptor agonists and antagonists. Highlights on structure-activity relationships have been included, when possible.

Cite this article as:

Lacivita Enza and Leopoldo Marcello, Selective Agents for Serotonin2C (5-HT2C) Receptor, Current Topics in Medicinal Chemistry 2006; 6 (18) . https://dx.doi.org/10.2174/156802606778522168