Mechanisms of Action and Targets for Actual and Future Antiplatelet Drugs

Title: Mechanisms of Action and Targets for Actual and Future Antiplatelet Drugs

Volume: 6 Issue: 6

Author(s): Kathleen Freson, Chantal Thys, Christine Wittevrongel and Chris V. Geet

Affiliation:

Keywords: cyclooxygenase, GPIIb/IIIa antagonists, Ticlopidine, monoclonal antibody, Thrombin Receptors

Abstract: Platelets are key players in arterial thrombosis and have become important targets in the primary and secondary prevention of atherothrombosis. Antiplatelet drugs are primarily directed against platelets and inhibit platelet activation by a number of different mechanisms. They are used for the prevention and treatment of thrombotic processes, especially in the arterial vascular system. Antiplatelet drugs in clinical use and experimental drugs are discussed.

Cite this article as:

Freson Kathleen, Thys Chantal, Wittevrongel Christine and Geet V. Chris, Mechanisms of Action and Targets for Actual and Future Antiplatelet Drugs, Mini-Reviews in Medicinal Chemistry 2006; 6 (6) . https://dx.doi.org/10.2174/138955706777435661