Abstract
Over the last few decades, the study of nanotechnology has grown exponentially. Nanotechnology bridges science, engineering and technology; it continues to expand in definition as well as practice. One sub-set of nanotechnology is bionanotechnology, this will be the focus of this review. Currently, bionanotechnology is being studied and exploited for utility within medicinal imaging, diagnosis and therapy in regard to cancer. Cancer is a world-wide health problem and the implication rate as well as the death rate increase year to year. However promising work is being done with gold nanoparticles for detection, diagnosis and targeted drug delivery therapy. Gold nanoparticles can be synthesized in various shapes and sizes, which directly correlates to the color; they can also be manipulated to carry various antibody, protein, plasmid, DNA or small molecule drug. Herein we summarize some of the very influential research being done in the field of Cancer Nanotechnology with an emphasis on gold nanoparticles.
Keywords: Cancer, gold, nanoparticles, targeted drug delivery, immunotherapy, antiangiogenic therapy, bioavailability, oligomers, fibroblast growth factor, antigen
Anti-Cancer Agents in Medicinal Chemistry
Title: Cancer Nanotechnology: Emerging Role of Gold Nanoconjugates
Volume: 11 Issue: 10
Author(s): Rachel A. Kudgus, Resham Bhattacharya and Priyabrata Mukherjee
Affiliation:
Keywords: Cancer, gold, nanoparticles, targeted drug delivery, immunotherapy, antiangiogenic therapy, bioavailability, oligomers, fibroblast growth factor, antigen
Abstract: Over the last few decades, the study of nanotechnology has grown exponentially. Nanotechnology bridges science, engineering and technology; it continues to expand in definition as well as practice. One sub-set of nanotechnology is bionanotechnology, this will be the focus of this review. Currently, bionanotechnology is being studied and exploited for utility within medicinal imaging, diagnosis and therapy in regard to cancer. Cancer is a world-wide health problem and the implication rate as well as the death rate increase year to year. However promising work is being done with gold nanoparticles for detection, diagnosis and targeted drug delivery therapy. Gold nanoparticles can be synthesized in various shapes and sizes, which directly correlates to the color; they can also be manipulated to carry various antibody, protein, plasmid, DNA or small molecule drug. Herein we summarize some of the very influential research being done in the field of Cancer Nanotechnology with an emphasis on gold nanoparticles.
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A. Kudgus Rachel, Bhattacharya Resham and Mukherjee Priyabrata, Cancer Nanotechnology: Emerging Role of Gold Nanoconjugates, Anti-Cancer Agents in Medicinal Chemistry 2011; 11 (10) . https://dx.doi.org/10.2174/187152011797927652
DOI https://dx.doi.org/10.2174/187152011797927652 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
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